Hydrocodone

Structure

Chemical Name Hydrocodone
Chemical Formula C18H21NO3
Molar Mass 299.4g/mol
Percent Composition by Mass

C x 18 =41.86%

H x 21 = 48.84%

N x 1 = 2.326%

O x 3 = 6.977%

Percent Composition by Number

C x 18 =72.20%

H x 21 = 7.084%

N x 1 = 4.679%

O x 3 = 16.03%

Melting Point 189°C
Boiling Point Not applicable
Appearance White to pale yellow crystals
Solubility Soluble in alcohol; insoluble in water
Density 1.32g/cm3
Type of Bonding Covalent
Natural Abundance Not applicable

Explanation of Structure

The hydrocodone structure is composed of four elements: carbon, hydrogen, nitrogen, and oxygen. These elements are held together through covalent bonds between the atoms. The chemical structure of hydrocodone is similar to codeine. Hydrocodone is one of the weaker opioid agonists. Opioid agonists are substances that act by attaching to specific proteins called opioid receptors, which are found in the brain, spinal cord, and gastrointestinal tract. When these drugs attach to certain opioid receptors in the brain and spinal cord they can effectively block the transmission of pain messages to the brain.