Properties


 

Chemically, Fluoxetine is chemically very inert.  It is not explosive or toxic, it is a synthetic designer compound.  Structurally it resembles Benadryl, the compound from which it was originally derived.

Prozac is classified as a “Selective Serotonin Reuptake Inhibitor.”  This means that it acts upon the neurotransmitters in a person’s brain.  Serotonin is one of the brain’s neurotransmitters that passes information about the body.  Serotonin is responsible for triggering sleep, telling us when we are in pain, and when we feel pleasure. When we feel an emotion and nerves somewhere in our body fire, this signal travels up into the brain.  In the brain, there are special nerve endings called the presynaptic and postsynaptic nerve endings.  The presynaptic nerve ending releases information in the form of Serotonin molecules.  These molecules then connect with the postsynaptic nerve ending, and the nerve impulse continues along the nerve.  The serotonin that was not used, that didn’t connect with the postsynaptic nerve, is either broken down or taken up by the presynaptic nerve. Fluoxetine interferes with this process by inhibiting the uptake of serotonin back into the presynaptic nerve ending.  Because the excess serotonin is not taken back up into the presynaptic nerve, it remains in the nerve ending.  This causes more serotonin to be taken up by the postsynaptic nerve, meaning that the person is receiving a sort of serotonin boost.  This boost has a very positive effect on the symptoms of depression, but scientists are still not sure exactly why. 

 

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