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INFORMATION 

Compound Name: Heroin


Formula: C21H23NO5

Picture of Heroin and Drug Paraphernalia


(picture from http://area51.upsu.plym.ac.uk/infoserv/drugs/graphical/grphopia.html)

Molar Mass: 369.42 grams


Historical Background/story of discovery: In 1803 morphine was isolated as a separate substance from opium, and in 1952 it was confirmed as a separate compound by Marshall Gates at the University of Rochester.  The Bayer Company of Germany developed heroin for the first time in 1898 when morphine was mixed with two moles of acetic anhydride.  Originally heroin was being used a narcotic analgesic, but its serious side effects out-weighted its value as a pain killer.


Melting point: 173 degrees Celsius


Boiling Point: 272-274 degrees Celsius


Where is it found:  Heroin is produced from poppy plants, and these plants are annual herb plants that are native to Southeastern Europe and Western Asia. This type of plant is also cultivated in Iran, Turkey, Holland, Poland, Romania, Czechoslovakia, Yugoslavia, India, Canada, as well as many Asian and Central and South American countries.


What is its natural abundance: Since heroin is not found in nature, but rather is produced from poppy plants, it does not have a natural abundance.  


How is it obtained: Heroin can be made by first obtaining morphine, which is an alkaloid found in opium (Opium is the dried milky exudate found in the unripe seedpods of poppy plants). The morphine should then be treated with acetic anhydride. The substance that is produced from this mixture, heroin, is four to eight times as potent as morphine.


Explanation of structure: A molecule of heroin is made up of 21 atoms of carbon, 23 atoms of hydrogen, 1 atom of nitrogen, and 5 atoms of oxygen.  There are six double bonds within each molecule, and the rest of the bonds are single bonds.  Percent composition by mass = 68.28% Carbon; 6.28 % Hydrogen; 3.79 % Nitrogen; 21.65 % Oxygen. Percent composition by number = 42 % Carbon; 46 % Hydrogen; 2 % Nitrogen; 10 % Oxygen. Covalent Bonding.

Chemical Properties:  Heroin is a white and sometimes brownish, odorless compound and is a highly addictive narcotic when abused.  When heroin is used, it creates a "high" by mimicking chemicals in the brain that block pain and induce a feeling of pleasure.  One gram of heroin dissolves in 1.5 mL of chloroform, 31 mL of alcohol, 100 mL of ether, and 1700 mL of water.

Reaction Tendencies:  None found

 

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